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Image Search Results
Journal: ACS chemical biology
Article Title: A Chemical Biology Solution to Problems with Studying Biologically Important but Unstable 9-O-Acetyl Sialic Acids
doi: 10.1021/acschembio.6b00928
Figure Lengend Snippet: Sialoglycan microarray binding specificity studies of human Siglec-9 (hSiglec-9-Fc, hSiglec-9), porcine torovirus hemagglutinin-esterase (PToV), and bovine coronavirus hemagglutinin-esterase (BCoV) (both PToV and BCoV were mutated to ablate their esterase activity) towards Neu5Ac9NAcα3Galβ4GlcβProNH2 (black columns), Neu5,9Ac2α3Galβ4GlcβProNH2 (gray columns), and Neu5Acα3Galβ4GlcβProNH2 (white columns) without esterase treatment (A) or treated with esterase active PToV (B).
Article Snippet: Glycan Microarray Screening Glycan microarrays were fabricated using epoxide-derivatized slides (Corning by Thermo Fisher Scientific) and
Techniques: Microarray, Binding Assay, Activity Assay